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\begin{document}

\title{Analysis of vaginal delivery outcomes in pregnant women during the
prevalence of COVID-19:a retrospective review of medical records}



\author[1]{Jing Liao}%
\author[1]{Xiaoyan He}%
\author[1]{Qing Gong}%
\author[1]{Lingyun Yang}%
\author[1]{Chunhua Zhou}%
\author[1]{Yuanzhen Zhang}%
\author[1]{Jiafu Li}%
\author[1]{Wei Zhang}%
\affil[1]{Wuhan University Zhongnan Hospital}%


\vspace{-1em}



  
  \date{June 15, 2024}


\begingroup
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\selectlanguage{english}
\begin{abstract}
Objective: To study the pregnancy outcomes of vaginal delivery and
neonatal prognosis during the epidemic of COVID-19, and to summarize the
management of vaginal delivery. Design: Retrospective review of medical
records Setting: Zhongnan Hospital of Wuhan University, Wuhan, China
Sample: Pregnant women (n=63) with vaginal delivery from January 20 to
March 02, 2020 Methods: Retrospectively analyzed the outcomes of vaginal
delivery in 10 pregnant women with clinical diagnosis of COVID-19 and 53
pregnant women without COVID-19 from January 20 to March 02, 2020. The
related laboratory tests, imaging tests and the SARS-CoV-2 nucleic acid
tests results were also analyzed in neonates delivered by pregnant woman
with clinical diagnosis of COVID-19. Main Outcome Measures: Delivery
outcomes and neonatal outcomes Results: (1) There were no significant
differences in gestational weeks, postpartum hemorrhage (245\selectlanguage{ngerman}±49.72ml vs
237±85.99ml), and perineal resection rates (10\% vs 7.55\%) between the
two groups. (2) There were no significant differences in birth weight of
neonates(3283±449g vs 3274±456g) and neonatal asphyxia between the two
groups. Results of the blood routine, throat swabs test for nucleic acid
of SARS-CoV-2 and chest radiograph of neonates delivered by pregnant
woman with clinical diagnosis of COVID-19 showed no signs of the
SARS-CoV-2 infection. Conclusions: Pregnant women with mild COVID-19 can
delivery vaginally without exacerbation of COVID-19 and without
increasing the risk of SARS-CoV-2 infection in the neonates. Keywords:
COVID-19\selectlanguage{english};outcomes of vaginal delivery\selectlanguage{english};neonatal prognosis\selectlanguage{english};management
Tweetable abstract\selectlanguage{english}:Pregnant women with mild COVID-19 can try vaginal
delivery%
\end{abstract}\selectlanguage{ngerman}%



\sloppy


\textbf{Introduction}

The first case of novel coronavirus-infected pneumonia (Corona Virus
Disease 2019, COVID-19) was discovered in Wuhan in December
2019\textsuperscript{\textbf{1}} , and the epidemic spread rapidly in
China and the whole world \textsuperscript{\textbf{2}} . Some scholars
in China have summarized the clinical manifestations of COVID-19 from
the aspects of patient epidemiology, symptoms and laboratory
examinations, and pulmonary imaging characteristics, it is indicated
that it can lead to severe lung disease in some
patients\textsuperscript{\textbf{3}} . And there is interpersonal
transmission during the incubation period of the
disease\textsuperscript{\textbf{4}} . At present, the prevention and
control of COVID-19 is still in a critical period in China and even in
the world. As the designated hospital for patients with COVID-19, Wuhan
University Zhongnan Hospital actively accepts and treats pregnant women
with confirmed or suspected COVID-19. In this study, we compared the
vaginal delivery outcomes between pregnant women with clinical diagnosis
of COVID-19 in the obstetric isolation ward of our hospital and pregnant
women without COVID-19 in the ordinary ward, and analyzed prognosis of
neonates delivered by pregnant woman with clinical diagnosis of
COVID-19. Indicate the effects of vaginal delivery on pregnant women and
newborns after a full assessment. In order to protect the perinatal
safety of this special group of pregnant women and avoid intrahospital
spread of COVID-19, according to the national guidelines for the
diagnosis and treatment of COVID-19 and the treatment process of the
clinical cases in our hospital, we summarized the experience of vaginal
delivery of pregnant women with confirmed or suspected COVID-19 during
this epidemic, and put forward the following suggestions for reference.

\textbf{Methods}

Study population

Collected 10 cases of pregnant women with clinical diagnosis of COVID-19
in the obstetric isolation ward and 53 cases of pregnant women without
COVID-19 in conventional wards of Zhongnan Hospital of Wuhan University,
Wuhan, China, from January 20 to March 2, 2020. All the cases were
vaginal delivery during the same period.

\emph{\textbf{Study design}}

In this study, we compared the ages of pregnant women, times of
pregnancy, gestational weeks, the amount~of postpartum hemorrhage,
perineal resection rates, birth weight of neonates and neonatal
asphyxia. The neonates delivered by pregnant woman with clinical
diagnosis of COVID-19 were transferred to the neonatal isolation ward,
at the same time, the results of blood routine test, throat swabs test
for nucleic acid of SARS-CoV-2 and chest radiograph were collected.

Diagnostic criteria

\textbf{Suspected cases} : Comprehensive analysis combining the
following epidemiological history and clinical manifestations, there is
any one of the epidemiological history or no epidemiological history,
and has two points of the clinical manifestations.

(1) Epidemiological history: Travel and residence history in Wuhan and
surrounding areas, or other communities with case reports within 14 days
before the onset. History of contact with cases of COVID-19 in the 14
days before the onset. Have contacted patients with fever or respiratory
symptoms from surrounding areas of Wuhan, or from communities with case
reports in the 14 days before the onset; Cluster onset.

(2) Clinical manifestations: Fever and / or respiratory symptoms.
Imaging features of the COVID-19. Normal or reduced white blood cell
count or reduced lymphocyte count in the early stages of onset.

\textbf{Clinical diagnosis cases} : The suspected cases with the imaging
features of pneumonia.

\textbf{Confirmed case} : Clinically confirmed cases or suspected cases,
with one of the following etiological evidence.

(1) Real-time fluorescent RT-PCR detection of SARS-CoV-2 nucleic acid
positive.

(2) The viral gene sequence is highly homologous to known
SARS-CoV-2.\textsuperscript{\textbf{5}}

Statistical analysis

Statistical analysis was performed using SPSS19.0 software. The counting
data was expressed by rate, using Fisher's exact probability method. The
measurement data was expressed by?x \selectlanguage{ngerman}±s, using \emph{t} test. The
difference was considered statistically significant at
\emph{P}\textless{}0.05.

\textbf{Results}

General information of the two groups

A total number of 88 pregnant women with confirmed or suspected COVID-19
were admitted to the obstetric isolation ward of Zhongnan Hospital of
Wuhan University. Among them 10 pregnant women with clinical diagnosis
of COVID-19 were vaginal delivery, the age of pregnant women delivered
by vaginal delivery range from 27 to 36 years old, the pregnant times
were 1-4, the number of deliveries were 0-2, the delivery weeks range
from 36 weeks 2 days to 40 weeks 2 days. The amount of postpartum
hemorrhage is 200-300ml. The results of relevant tests and lung computed
tomography (CT) were detailed in Table 1.

In the same period, 53 pregnant women without COVID-19 were also vaginal
delivery in the ordinary ward, the age ranged from 21 to 37 years old,
the pregnancy times were 1-4, the number of deliveries were 0-1, the
delivery weeks range from 31 weeks 1 days to 42 weeks. Pregnant women
with clinical diagnosis COVID-19 are older than those without COVID-19
(\emph{P} = 0.042). Pregnant women with clinical diagnosis COVID-19 have
more pregnancy times than those without COVID-19 (\emph{P} = 0.009).
There was no statistically significant difference in the gestational
weeks (\emph{P} = 0.921) and number of deliveries (\emph{P} = 0.118)
between the two groups. (Table 2)

Comparison of vaginal delivery outcomes between the two groups

There was no significant difference between the two groups of pregnant
women in terms of premature rupture of membranes, premature delivery,
neonatal asphyxia, amniotic fluid pollution, the amount~of postpartum
hemorrhage, and perineal lateral resection rate. (Table 3)

\emph{\textbf{Analysis of the results of neonates delivered by pregnant
woman with clinical diagnosis} \textbf{COVID-19 in isolation ward}}

Among the 10 cases of neonates delivered by pregnant women with clinical
diagnosis COVID-19 in the isolation ward, 3 cases were self-discharged
from the hospital due to family refusal of neonatal pediatric treatment,
and 7 cases were delivered to neonatal isolation according to management
principles of neonates delivered by infected pregnant women. Among them,
6 were term infants and 1 was premature infants. The blood routine tests
of the 7 neonates were normal, and throat swabs test for nucleic acid of
SARS-CoV-2 were negative for twice. The result of chest radiography was
considered to be hyaline membrane disease for one case, which improved
after treatment with pulmonary surfactant substitutes and symptomatic
support. The other neonates had the normal chest radiograph results.
(Table 4)

\textbf{Discussion}

Main Findings

In this retrospective study, we analyzed and compared the outcomes of
vaginal delivery between 10 pregnant women with clinically confirmed
COVID-19 in the isolation ward and 53 pregnant women without COVID-19 in
the general ward during the same period, and analyzed neonatal
prognosis. The research showed there were no significant differences in
gestational weeks, postpartum hemorrhage, perineal resection rates,
neonatal weight, and neonatal asphyxia rates between the two groups. 10
neonates were delivered by pregnant women with clinical diagnosis
COVID-19. Of these, 3 cases were self-discharged from the hospital
because of refusal of neonatal pediatric treatment, although being
informed of relevant risks. and 7 neonates were tested for SARS-CoV-2
nucleic acid throat swabs twice in succession, all of which were
negative. Only 1 neonate was considered hyaline membrane disease by
chest X-rays, No SARS-CoV-2 infection was detected in the chest
radiographs of the remaining neonates.

Strengths and Limitations

As a COVID-19-designated hospital in Wuhan, the pregnant women with
suspected and confirmed COVID-19 were admitted to our hospital. During
the epidemic, cesarean section and general anesthesia were preferred to
ensure that the delivery process is controllable, and to reduce
emergency respiratory problems and reduce the risk of exposure to
others. But the effects of these measures have not been fully
proven\textsuperscript{6,7,8}. During the epidemic, choosing~cesarean
section blindly will cause~the long-term~adverse~effects on women
undoubtedly. This study analyzed the pneumonia conditions, delivery
conditions, delivery outcomes, and neonatal infections in pregnant women
with COVID-19, and evaluate~the effect~ of vaginal delivery on pregnant
women with COVID-19 and their newborns. Based on the above data, we
provided more suggestions for the choice of delivery mode for pregnant
women during the COVID-19 epidemic, summarized the methods of infection
prevention during vaginal delivery and provide effective measures to
avoid medical staff infection.

However, this study is limited by the small sample size, as the number
of pregnant women with clinically confirmed COVID-19 underwent vaginal
delivery is relatively small. This group of pregnant women are in
accordance with the clinical diagnostic criteria for COVID-19 in China,
but the pathogenic diagnosis is negative, but the false-negative results
of SARS-CoV-2 nucleic acid throat swabs could not be excluded
completely. For clinically diagnosed cases, close follow-up observation
would be required. In addition, for pregnant women with COVID-19
underwent vaginal delivery, it can provide an indirect etiology basis
for the existence of neonatal infection if the SARS-CoV-2 nucleic acid
detection of amniotic fluid, vaginal secretions and perianal secretions
can be performed.

Interpretation

\textbf{1. Delivery Methods for pregnant womenwith confirmed or
suspected COVID-19}

As we all known, the COVID-19 is highly infectious, and due to the
pathophysiological changes during pregnancy, the SARS-CoV-2 infection in
pregnancy women is easy to progress to severe disease, and the risk of
adverse pregnancy outcomes is high\textsuperscript{\textbf{9}} . In
principle, caesarean section is recommended to terminate pregnancy
during the epidemic period\textsuperscript{\textbf{6}} . In the
following cases, caesarean section should be the main choice: With
pregnancy-related complications and has indications for emergency
cesarean section; Already in labor, but the conditions for vaginal
delivery are not good enough to make a short-term vaginal delivery;
Pregnant women with severe or critical
COVID-19\textsuperscript{\textbf{5}} cannot tolerate vaginal delivery.

In our research, the 10 cases of pregnant women with clinical diagnosis
COVID-19 in isolation ward terminated pregnancy by vaginal delivery were
classified as mild patients in combination with the results of
laboratory and imaging examination. After admission, they already had
regular uterine contraction, the fetal head was well connected, the
fetal presentation was low, and all of them have officially entered the
labor process. Therefore, we believe that there is no indication for
cesarean section. The primipara is in the late stage of the active
period or enters the second stage of labor, the relationship of fetal
head and pelvic is good, it is estimated that the vaginal delivery can
be performed in a short time. The multipara has already entered the
labor process, the relationship of fetal head and pelvic relationship is
good, it is estimated that the vaginal delivery can be performed within
a short time. Vaginal delivery can also be selected in the above cases.
Before deciding on the delivery method, in addition to the rapid
improvement of routine laboratory tests, SARS-CoV-2 nucleic acid throat
swab test, serum SARS-CoV-2 antibody test, and other respiratory
pathogen detection which is helpful for differential diagnosis should be
also finished. If necessary, perform bedside ultrasound to assess the
situation of the fetus and appendages. Pregnant women are the same as
non-pregnant patients. X-rays and CT are important methods for
diagnosing COVID-19 and evaluating the condition. When necessary, check
the lung CT (radiation low-dose screening for lung CT with conditions
available) under the radiation protection of the pregnant woman with
abdominal lead covering, which can be used to evaluate the lung
lesions\textsuperscript{\textbf{10}} .

\textbf{2. Management of pregnant women with confirmed or suspected
COVID-19 during vaginal delivery and the pregnancy outcomes.}

During the course of labor, due to the intolerability of the labor
pains, the cooperation degree of the pregnant women is reduced, they may
cry, cough, hyperventilate and so on, thus, a large number of droplets
and aerosols are generated, which increases the exposure and infection
possibility of the medical staff. Thus we should strengthen the
humanistic care for pregnant women, actively give them guidance, comfort
and encouragement in the process of delivery, effectively communicate
with pregnant women, stabilize the mood of pregnant women, and help them
to eliminate their fear. Pregnant women with confirmed or suspected
COVID-19 were given nasal catheter oxygen inhalation immediately after
entering the isolation delivery room (or isolation ward), and wore
medical surgical masks\textsuperscript{\textbf{11}} . Provide energy
support, free position can be used to promote vaginal delivery and try
to alleviate the pain and discomfort of pregnant women. Continuous ECG
monitoring if necessary. In order to avoid too long labor process caused
excessive physical consumption of pregnant women and increase the burden
of cardiopulmonary function, on the premise of ensuring the safety of
the mother and fetus, the labor process should be shortened as much as
possible to reduce the exposure time of the fetus in the obstetric
canal. If necessary, episiotomy, forceps operation and vacuum extraction
can be used as midwifery. Timely compress and hemostasis the perineal
wound to reduce the contact between fetus and mother blood. In the
process of delivery, pay attention to avoid the pollution caused by
amniotic fluid and blood splashing, absorbent mattress mats can be laid
on the floor around the delivery bed, and disposable sterile liquid
storage bag can be placed under the buttocks of pregnant women to
collect amniotic fluid and blood. After delivery of the fetus, oxytocin
should be used as early as possible to promote uterine contraction, if
necessary, ergometrine and/or long-acting oxytocin should be used in
time to promote uterine contraction. Take other necessary measures to
actively prevent postpartum hemorrhage according to the situation. After
the delivery of fetus and placenta, routinely check the soft birth canal
and suture the perineal incision wound or perineal laceration in time.
Observed in the isolation room for 2 hours after delivery, or in the
isolation ward under the supervision of the midwife for 2 hours.
Strictly monitor vital signs, observe uterine contractions and vaginal
bleeding, meanwhile, provide postnatal care for parturient women.

In this retrospective study, 10 pregnant women in the isolation ward of
Obstetrics had no significant abnormality in the continuous monitoring
of vital signs and blood oxygen saturation during the labor process, and
the labor process was smooth. The second labor process was 10 minutes to
1 hour, no forceps and fetal head suction attendant midwifery. Only 3
cases of these primiparas underwent perineal resection to shorten the
labor process and avoid severe perineal lacerations considering the
possibility of fetal overgrowth. There was no significant difference in
the amount of postpartum hemorrhage between the pregnant women with
confirmed or suspected COVID-19 and the pregnant women without COVID-19.
During the postpartum observation, no exacerbation of respiratory
symptoms was observed in all cases. However, one patient considered
acute fatty liver during pregnancy after the emergency vaginal delivery,
and the lung CT showed the progression of viral pneumonia, which
improved after the treatment in ICU. Therefore, it is necessary to
strengthen the monitoring of such patients after delivery, just as
important, the infectious diseases indicators and lung CT should be
rechecked in time. At sometimes, it is necessary to carry out
multidisciplinary consultation and cooperation including respiratory
department, infection department and ICU to ensure perinatal safety.

\textbf{3. Management and outcomes of neonates delivered by pregnant
women with confirmed or suspected COVID-19}

Studies have shown that there was no clinical, laboratory or
radiological evidence of SARS coronavirus infection in 12 neonates
delivered by pregnant women during the outbreak period of SARS in
2003\textsuperscript{\textbf{12,13}} . Previous studies in our hospital
have shown that there is no evidence for intrauterine infection caused
by vertical transmission in women who develop COVID-19 in late
pregnancy\textsuperscript{\textbf{8}} . However, in order to reduce the
risk of neonatal infection caused by mother-to-child contact, it is
recommended that neonates delivered by pregnant woman with confirmed or
suspected COVID-19 should have their umbilical cords cut and cleaned as
early as possible to reduce the exposure time. The Apgar score of the
neonate was normal or returned to normal after the initial
resuscitation, after routine treatment by the midwife, the neonate was
delivered to the pediatrician outside the isolation delivery room (or
outside the isolation ward) and immediately placed in a transfer
incubator equipped with ECG monitoring equipment, and then transferred
to neonatal isolation ward for observation and treatment through a
special passage.

\textbf{4. Protective measures during vaginal delivery of pregnant women
with confirmed or suspected COVID-19}

The SARS-CoV-2 is mostly transmitted through respiratory tract and
exposed to infection. In a recent retrospective clinical study, it has
been pointed out that the hospital related transmission of COVID-19 is
not uncommon \textsuperscript{\textbf{14}} . Therefore, environmental
management and personal protection should be carried out in the vaginal
delivery of pregnant women with confirmed or suspected COVID-19.

If the department of obstetrics already has a negative pressure
isolation delivery room, pregnant women with confirmed or suspected
COVID-19 should, in principle, complete vaginal delivery in the negative
pressure isolation delivery room. If the conditions are limited, there
is no negative pressure isolation delivery room, the delivery can also
be completed in a single isolated delivery room. The isolation delivery
room should be provided with three areas and three passages, the three
areas refer to clean areas, semi-polluted areas, and polluted areas, the
three passages refer to medical personnel passages, maternal
transport-only passages, and dirt passages. The central air conditioning
circulation system should be closed, use plastic sheeting to close each
vent, and use electric heating equipment to maintain the indoor
temperature if necessary. The delivery room should be simplified with
only necessary facilities such as delivery bed and neonatal radiation
table. The delivery room should be simplified with only necessary
facilities such as delivery bed and neonatal radiation table. In case of
limited conditions or emergency situations, vaginal delivery can be
carried out in isolation ward under strict protection.

In the process of delivery, the number of attendants should be as few as
possible, and the number of medical staff required for treatment should
be reduced to a minimum in the isolation delivery room (or isolation
ward). Only one senior midwife and one first-line obstetrician stay in
the isolation delivery room, with two-level protection, if conditions
permit, three-level protection can be provided, i.e. wearing positive
pressure headgear or full-breathing protector, and the midwife can wear
disposable waterproof overshoes. The second-line obstetrician and
pediatrician can take two-level protective measures and stand by outside
the isolation delivery room (or isolation ward) to prepare for the
emergency situation of pregnant women and newborns.

Placental tissue is disposed according to the principle of infectious
biological waste disposal. It is packed in double-layer yellow medical
garbage bags in the isolation delivery room (or the isolation ward), the
two-layer garbage bags are sealed in layers to ensure tight sealing, and
marked with ``COVID-19'' and ``placenta'', after the surface was sprayed
with 1000mg/L chlorine-containing disinfectant. Reusable medical
equipment can be reused in a special instrument box, after 30 minutes of
immersion in 2000mg/L chlorine-containing disinfectant, sealed in layers
with a double-layer yellow medical garbage bag, and marked with
``COVID-19'', collected and cleaned by a special person, then complete
the subsequent sterilization. If the delivery is completed in an
isolated delivery room, the indoor air is continuously fumigated and
sterilized using a vaporized hydrogen peroxide machine in the closed
state for 2 hours; if the delivery is completed in an isolated ward, the
indoor air is disinfected by a human-machine coexisting air disinfection
machine for 4 hours. The indoor floor should be cleaned with 2000mg/L
chlorine-containing disinfectant, and the fixed facilities in the
isolation delivery room (or the isolation ward) should be wiped with
1000mg/L chlorine-containing disinfectant. The surface that was in
contact with the patient's body fluids, blood and other contaminated
surfaces shall be treated with 2000mg/L - 5000mg/L chlorine-containing
disinfectant. Indoor precision medical supplies, such as ECG monitors,
stethoscopes, fetal heart monitors, infusion pumps, etc. can be
thoroughly wiped and disinfected with 75\% ethanol solution or 1000mg/L
chlorine-containing disinfectant.

\textbf{Conclusion}

This is the first report to retrospectively evaluate the pregnancy
outcomes of vaginal delivery and neonatal prognosis during the epidemic
of COVID-19.On the premise of full evaluation of the vaginal delivery
conditions and strict protection measures, pregnant women with mild
COVID-19 can try vaginal delivery without exacerbation of COVID-19 and
without increasing the risk of SARS-CoV-2 infection in the neonates.

\textbf{Acknowledgements}

This study was supported by Hubei science and technology department
emergency project (Perinatal management strategies and mother-to-child
transmission of pregnant women infected with 2019-nCoV No2020FCA011)

\textbf{Disclosure of Interests}

The authors report no conflict of interest. Completed disclosure of
interest forms are available to view online as supporting information.

\textbf{Contribution to authorship}

JL and XH made substantial contributions to the study concept, design
and writing up of the work. QG took part in the conception, planning. CZ
and LY made contributions to data acquisition, analysis, and
interpretation. YZ, JL and WZ made substantial revisions to the
manuscript.

\textbf{Details of Ethics Approval}

The study was approved by the medical ethics committee of Zhongnan
Hospital of Wuhan University (No2020078, 19 \textsuperscript{th} March
2020)

\textbf{Funding}

Hubei science and technology department emergency project

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\textbf{Table 1} \textbf{Clinical, laboratory and imaging
characteristics of pregnant women with clinical diagnosis of COVID-19 in
obstetric isolation ward}\selectlanguage{english}
\begin{longtable}[]{@{}lllllllllll@{}}
\toprule
\begin{minipage}[b]{0.07\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[b]{0.07\columnwidth}\raggedright\strut
P 1\strut
\end{minipage} & \begin{minipage}[b]{0.07\columnwidth}\raggedright\strut
P2\strut
\end{minipage} & \begin{minipage}[b]{0.07\columnwidth}\raggedright\strut
P3\strut
\end{minipage} & \begin{minipage}[b]{0.07\columnwidth}\raggedright\strut
P4\strut
\end{minipage} & \begin{minipage}[b]{0.07\columnwidth}\raggedright\strut
P5\strut
\end{minipage} & \begin{minipage}[b]{0.07\columnwidth}\raggedright\strut
P6\strut
\end{minipage} & \begin{minipage}[b]{0.07\columnwidth}\raggedright\strut
P7\strut
\end{minipage} & \begin{minipage}[b]{0.07\columnwidth}\raggedright\strut
P8\strut
\end{minipage} & \begin{minipage}[b]{0.07\columnwidth}\raggedright\strut
P9\strut
\end{minipage} & \begin{minipage}[b]{0.07\columnwidth}\raggedright\strut
P10\strut
\end{minipage}\tabularnewline
\midrule
\endhead
\begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
\textbf{Date of delivery}\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
1.29\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
2.1\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
2.4\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
2.9\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
2.12\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
2.14\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
2.15\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
2.17\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
2.29\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
3.2\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
\textbf{Age}\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
29\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
36\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
30\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
36\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
36\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
30\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
33\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
33\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
27\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
29\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.09\columnwidth}\raggedright\strut
\textbf{Delivery weeks} \textbf{(weeks+days)}\strut
\end{minipage} & \begin{minipage}[t]{0.09\columnwidth}\raggedright\strut
40+4\strut
\end{minipage} & \begin{minipage}[t]{0.09\columnwidth}\raggedright\strut
39\strut
\end{minipage} & \begin{minipage}[t]{0.09\columnwidth}\raggedright\strut
39+5\strut
\end{minipage} & \begin{minipage}[t]{0.09\columnwidth}\raggedright\strut
37+6\strut
\end{minipage} & \begin{minipage}[t]{0.09\columnwidth}\raggedright\strut
38+1\strut
\end{minipage} & \begin{minipage}[t]{0.09\columnwidth}\raggedright\strut
40+1\strut
\end{minipage} & \begin{minipage}[t]{0.09\columnwidth}\raggedright\strut
39+4\strut
\end{minipage} & \begin{minipage}[t]{0.09\columnwidth}\raggedright\strut
36+2\strut
\end{minipage} & \begin{minipage}[t]{0.09\columnwidth}\raggedright\strut
40+2\strut
\end{minipage} & \begin{minipage}[t]{0.09\columnwidth}\raggedright\strut
37+2\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
\textbf{Pregnany times}\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
1\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
2\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
2\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
3\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
4\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
1\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
2\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
3\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
4\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
2\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
\textbf{Number of deliveries}\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
0\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
1\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
0\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
0\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
1\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
0\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
1\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
1\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
2\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
1\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
\textbf{Clinical} \textbf{characteristic}\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
Fever\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
Yes\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
Yes\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
Yes\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
Yes\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
Yes\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
Cough\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
Yes\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
Yes\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
Yes\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
Sore throat\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
Yes\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
Dyspnea\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
Chest pain\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
Yes\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
Myalgia\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
Diarrhoea\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
\textbf{Laboratory characteristic}\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
White blood cell count (\selectlanguage{ngerman}×10\selectlanguage{english}9 cells per L)\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
9.42\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
8.68\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
12.53\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
10.86\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
9.45\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
9.38\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
10.61\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
11.67\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
8.75\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
9.63\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
Lymphocyte count (\selectlanguage{ngerman}×10\selectlanguage{english}9 cells per L)\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
1.13\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
2\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
1.47\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
0.85 \textbf{|}\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
1.38\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
1.22\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
1.64\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
1.5\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
0.74 \textbf{|}\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
1.91\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
Lymphocyte ratio (\%)\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
12 \textbf{|}\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
23\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
11.7 \textbf{|}\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
7.8 \textbf{|}\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
14.7 \textbf{|}\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
13 \textbf{|}\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
15.5 \textbf{|}\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
12.8 \textbf{|}\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
8.5 \textbf{|}\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
19.8 \textbf{|}\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
C-reactive protein (mg/L)\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
57.2 \textbf{|}\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
/\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
2.86\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
/\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
2.1\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
3.99\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
2.5\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
41.2 \textbf{|}\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
88.09 \textbf{|}\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
32.09 \textbf{|}\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
SARS-CoV-2 nucleic acid tests\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
Lung CT\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
+\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
+\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
+\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
+\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
+\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
+\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
+\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
+\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
+\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
+\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
Perineal incision\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
Yes\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
Yes\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
Yes\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
No\strut
\end{minipage}\tabularnewline
\begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
Postpartum hemorrhage(ml)\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
200\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
300\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
300\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
300\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
200\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
300\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
200\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
200\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
200\strut
\end{minipage} & \begin{minipage}[t]{0.07\columnwidth}\raggedright\strut
250\strut
\end{minipage}\tabularnewline
\bottomrule
\end{longtable}

\textbf{Table 2 Comparison of general information between pregnant women
with clinical diagnosis COVID-19 and pregnant women without COVID-19}\selectlanguage{english}
\begin{longtable}[]{@{}lllll@{}}
\toprule
& pregnant women with suspected COVID-19 & pregnant women without
COVID-19 & \emph{t/Fisher exact probability} & \emph{P
value}\tabularnewline
\midrule
\endhead
Perineal incision rate & 30\% (3/10) & 37.74\% (20/53) & - &
0.734\tabularnewline
amniotic fluid pollution & 20\% (2/10) & 22.64\% (12/53) & - &
1.000\tabularnewline
Postpartum hemorrhage(ml) & 245\selectlanguage{ngerman}±49.72 & 237\selectlanguage{ngerman}±85.99 & 0.258 &
0.797\tabularnewline
neonatal asphyxia & 0(0/10) & 4 & - & 1.000\tabularnewline
premature delivery rate & 10\% (1/10) & 7.55\% (4/53) & - &
1.000\tabularnewline
birth weight of neonates(g) & 3283\selectlanguage{ngerman}±449 & 3274\selectlanguage{ngerman}±456 & 0.059 &
0.953\tabularnewline
\bottomrule
\end{longtable}

\textbf{Table 3 Comparison of vaginal delivery outcomes between pregnant
women with clinical diagnosis COVID-19 and pregnant women without
COVID-19}

\textbf{Table 4 Results of neonates delivered by pregnant women with
clinically confirmed COVID-19}\selectlanguage{english}
\begin{longtable}[]{@{}llllllll@{}}
\toprule
& P4 & P5 & P6 & P7 & P8 & P9 & P10\tabularnewline
\midrule
\endhead
White blood cell count (\selectlanguage{ngerman}×10\selectlanguage{english}9 cells per L) & 12.47 & 13.77 & 12.13 &
13.09 & 10.62 & 11.93 & 11.0\tabularnewline
Lymphocyte count (\selectlanguage{ngerman}×10\selectlanguage{english}9 cells per L) & 2.25 & 4.3 & 2.45 & 3.88 & 2.12 &
2.72 & 2.56\tabularnewline
Lymphocyte ratio (\%) & 18.80 & 31.2 & 2.20 & 29.7 & 20 & 22.80 &
23.2\tabularnewline
SARS-CoV-2 nucleic acid tests & No & No & No & No & No & No &
No\tabularnewline
chest X-rays & - & - & - & - & - & - & hyaline membrane
disease\tabularnewline
\bottomrule
\end{longtable}

\selectlanguage{english}
\FloatBarrier
\end{document}

