Elecsys Immunoassay sFlt-1/PlGF ratio (Roche Diagnostics)
The Elecsys sFlt-1/PlGF ratio is derived by combining the results from
two CE-approved sandwich electrochemiluminescence immunoassays. The
analysis turnaround time is 18 minutes. The test requires a large-scale
laboratory analyser and is not a point-of-care test. The Elecsys sFlt-1
assay has a lower limit of detection of 10pg/ml and a range of 10 –
85,000pg/ml. The Elecsys PlGF assay has a lower limit of detection of
3pg/ml and a range of 3 to 10,000pg/ml. The National Institute for
Health and Care Excellence recommends use as a rule-out test for
suspected pre-eclampsia between 20 and 34+6 weeks’
gestation, at a threshold of ≤ 38.9