Complications Beta-blockers CCB Methyldopa Observations
Severe hypertension * decreases decreases decreases Better results with labetalol and nifedipine.
Preeclampsia with or without severity criteria decreases decreases No changes CSR 4 shows increase preeclampsia with CCB.
Premature birth decreases decreases No changes
Placental abruption No changes No changes No changes The study by Tita et al 3 (beta-blockers and CCB) showed benefits when adding this variable to the set of primary results.
Fetal or perinatal death No changes No changes No changes The study by Tita et al 3 (beta-blockers and CCB) showed benefits when adding this variable to the set of primary results.
Fetal complications † No changes No changes No changes CSR4 shows decreased neonatal respiratory distress when using beta-blockers.
Small for gestational age No changes No changes No changes
Caesarean section No changes No changes Increases