Data analysis
Power analysis was not performed since this is a pilot study.
Statistical analysis was performed using the free software R
(www.r-project.org). The Wilcoxon Rank Test was used for comparisons
between pre- and post treatment values. P-value significance was set at
<0.05. Patient number 4 was excluded from analysis of BALF
data as he did not undergo the follow-up bronchoscopy. Patient number 5
was excluded from all analyses as follow-up data was missing, due to a
possible adverse event.