Parameter Unit Description Estimate 95% CI
Vmax mg/h/kg Maximum elimination rate 2.41 2.36–3.61
Vc L/kg Central volume 0.39 0.277–0.446
ka /h Absorption rate constant 5.07 3.17–5.98
Vp L/kg Peripheral volume 0.89 0.602–0.934
Q L/h/kg Inter-compartment clearance 0.65 0.465–0.765
F % Bioavailability 28.0 25.9–35.0
KM µg/kg Amount of half Vmax 616 478–972
Proportional error % Proportional residual error 45 39–50
Additive error ng/ml Additive residual error 4.7 1.4–2.8
IIV(Vmax) % Inter-individual variability Vmax 28.2 24.4–32.2