Figure legends.
Figure 1 . Distribution of fasting plasma concentrations
of PCSK9 in 134 pregnant women . Levels of PCSK9 were measured using a
sandwich ELISA in plasma samples obtained after women fasted overnight;
see Subjects and Methods for details.
Figure 2. Box plot showing exposure to
PM10, PM2.5, and NO2.Exposure was evaluated as the mean from one week before the visit (week
0–1) and 12 weeks earlier (week 0–12). PM10,
PM2.5, and NO2 were averaged over mean
daily concentrations.
Figure 3 . Interaction effect of PM2.5 and
PCSK9 levels on gestational age . Strength of association between PCSK9
and gestational age at four selected levels of PM2.5 (25°, 50°, 75°, and
95° percentile). Estimates were calculated from multivariate models
adjusted for birth mode (spontaneous, urgent, and elective cesarean) and
interaction between PCSK9 and PM2.5 at 0–10 weeks; the P-value for the
interaction term was = 0.0258. Adjusted β regression coefficients are
reported for 1 mg/m3 increase in PCSK9 concentration.
Table 1. Clinical characteristics of the pregnant women and
newborns