Acknowledgements
Author contributions: All authors contributed to experiment design, analysis of results and interpretation of data. KS and SS conducted bench work and writing; GM contributed to methods development and adaptation; APS did conceptualization of the work, analysis of physiological relevance of the results, and writing.
Funding: This work was supported by the Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram -695011, India [grant numbers: Ph.D/2005/01/Sangeetha SR, Ph.D/2013/05/Karthi S].