Development of a mutation hotspot detection kit for the phenylalanine hydroxylase gene by ARMS-PCR combined with fluorescent probe technology
Rong Qiang1,2,3, Lin Wang, JinHua He, Wei Jie Xu5, Wei Li3, Na Cai3, Xiao Bin Wang3, RuiXue Zhang 3, Li Ping Zhang3 , Xiao Ping Ma 3,Chen Wei3, ChengRong Song3, WenWen Yu3, Xiang Wang1,2, Xu LI1,2,*
1Center for Translational Medicine, First Affiliated Hospital of Xi’an Jiaotong University, Xi’an 710061, P. R. China
2Key Laboratory for Tumor precision Medicine of Shaanxi Province, First Affiliated Hospital of Xi’an Jiaotong University, Xi’an 710061, P. R. China
3Medical Heredity Research Center, Northwest Women’s and Children’s Hospital, Shaanxi, Xi’an 710003, P. R. China
4 Department of Laboratory Medicine, Central Hospital of Panyu District, Guangzhou, Guangdong 511400, P. R. China
5 Guangzhou Lanji Biotechnology Co., Ltd., Guangzhou, Guangdong 510665, P. R. China
ΔThese authors contributed equally to this study.
* Corresponding author: Xu Li
First Affiliated Hospital of Xi’an Jiaotong University
Xi’an 710061, P. R. China
E-mail: lixu56@mail.xjtu.edu.cn