Development of a mutation hotspot detection kit for the
phenylalanine hydroxylase gene by ARMS-PCR combined with fluorescent
probe technology
Rong Qiang1,2,3, Lin Wang3Δ, JinHua
He4Δ, Wei Jie Xu5, Wei Li3, Na Cai3, Xiao Bin
Wang3, RuiXue Zhang 3, Li Ping Zhang3 , Xiao Ping Ma 3,Chen Wei3, ChengRong Song3, WenWen
Yu3, Xiang Wang1,2, Xu
LI1,2,*
1Center for Translational Medicine, First Affiliated
Hospital of Xi’an Jiaotong University, Xi’an 710061, P. R. China
2Key Laboratory for Tumor precision Medicine of
Shaanxi Province, First Affiliated Hospital of Xi’an Jiaotong
University, Xi’an 710061, P. R. China
3Medical Heredity Research Center, Northwest Women’s
and Children’s Hospital, Shaanxi, Xi’an 710003, P. R. China
4 Department of Laboratory Medicine, Central Hospital
of Panyu District, Guangzhou, Guangdong 511400, P. R. China
5 Guangzhou Lanji Biotechnology Co., Ltd., Guangzhou,
Guangdong 510665, P. R. China
ΔThese authors contributed equally to this study.
* Corresponding author: Xu Li
First Affiliated Hospital of Xi’an Jiaotong University
Xi’an 710061, P. R. China
E-mail: lixu56@mail.xjtu.edu.cn