Reference Follow-up time P value
MEDICATION PROBLEMS MEDICATION PROBLEMS MEDICATION PROBLEMS MEDICATION PROBLEMS
Bergkvist et al, 2009 At discharge Patients with ≥ 1 medication error (n/N, %): Intervention=14/52 (27%); Control=23/63 (37%) NRa
Patients with ≥ 3 medication errors (n/N, %): Intervention=3/52 (6%); Control=11/63 (17%) NR
Patients with ≥ 5 medication errors (n/N, %): Intervention=1/52 (2%); Control=5/63 (8%) NR
Medications with medications errors (n/N, %): Intervention=25/520 (5%); Control=66/549 (12%) NR
Boockvar et al, 2006 At discharge Drug Discrepancy Risk Index (mean, sd, N): Post =11.3 (5.9), N=87; Pre=9.1 (5.1), N=81 p=0.004
Discrepancy-Related Adverse Drug Events (n, %): Post=1 (2.3%); Pre=10 (14.5%) NR
Crotty et al, 2004 At discharge Discrepancy between medication summary and medication sent (n/N, %): Intervention=32/56 (57%); Control=26/54 (48%) p=0.259
Medication adverse event or interaction (n/N, %): Intervention=9/56 (16%); Control=6/54 (11%) p=0.581
At 8 weeks Adverse drug event (n/N, %): Intervention=20/44 (45%); Control=19/44 (43%) p=0.830
Medication Appropriateness lndex (mean, 95% confidence interval, N): Intervention=2.5 (1.4-3.7), N=44; Control=6.5 (3.9-9.1), N=44 NR
Elliott et al, 2012 12 weeks Patients with ≥ 1doses missed or significantly delayed within 24h of discharge (n/N, %): Post=6/226 (3%); Pre=37/202 (18%) p<0.001
Number of medications with ≥1 doses missed or significantly delayed within 24h of discharge (total n medications, N patients, %): Post=9/226 (4%); Pre=75/202 (37%) NR
Midlov et al, 2012b At discharge Patients with ≥1 medication error (n/N, %): Intervention 1=27/49 (55%); Intervention 2=10/28 (36%); Control=16/32 (50≥%) NR
Patients with ≥3 medication errors (n/N, %): Intervention 1=6/49 (12%); Intervention 2=0/28 (0%); Control=5/32 (16%)
Int 1: p=0.41 Int 2: p=0.048
Mean number of errors per patient (mean, N)c: Intervention 1=1.1, N=49; Intervention 2=0.46, N=28; Control=1.5, N=32 NR
Ward et al, 2008 At discharge Patients with 0 (none) omitted medication (n/N, %): Intervention=0/10 (0%); Control=3/10 (30%) p>0.05d
Patients with 1-3 omitted medications (n/N, %): Intervention=8/10 (80%); Control=3/10 (30%)
Patients with 4-8 omitted medications (n/N, %): Intervention=2/10 (20%); Control=4/10 (40%)
Number of omitted medication doses per patient (mean, sd, N): Intervention=3.8 (2.49), N=10; Control=2.9 (2.88), N=10 NR
Medications with 1 omitted dose (n/N, %): Intervention=24/29 (83%); Control=29/29 (100%) p>0.05d
Medications with 2 omitted doses (n/N, %): Intervention=3/29 (10%); Control=0/29 (0%)
Medications with 4 omitted doses (n/N, %): Intervention=2/29 (7%); Control=0/29 (0%)
Doses of omitted medications with potential low negative consequences (n/N, %): Intervention=5/38 (13%); Control=12/29 (41%) p>0.05d
Doses of omitted medications with potential medium negative consequences (n/N, %): Intervention=18/38 (47%); Control=10/29 (34%)
Doses of omitted medications with potential high negative consequences (n/N, %): Intervention=15/38 (39%); Control=7/29 (24%)
ADVANCE DIRECTIVES ADVANCE DIRECTIVES ADVANCE DIRECTIVES ADVANCE DIRECTIVES
Harvey et al, 2014 At 6 months Caregiver/patient satisfied with the Advanced Care Planning (n/N, %): Intervention=17/20 (85%); Control=9/24 (38%) p=0.002
Participation in at least 1 family meeting and Advanced Care Planning discussion (n/N, %): Intervention=36/54 (67%); Control=Not assessed N/Ae
Documentation of advanced directives (n/N, %): Intervention=36/54 (67%); Control=Not assessed N/Ae
Zafirau et al, 2012 At 30 days Advance directives status discordance between hospital and LTCF (%, N): Post=16.3%, N=117; Pre=26.7%, N=130 p=0.038
Do-Not-Resuscitate orders discordance between hospital and LTCF (%, N): Post=27.1%, N=117; Pre=40%, N=130 NR