Abstract
Cardiovascular diseases (CVDs) cause massive morbidity and mortality. In
recent years, natural small-molecule therapeutics have attracted much
attention for their significant efficacy. Articles have been published
to study the intervention of natural drugs (including monomers,
compounds, compound and neo-combinations) on one type of cardiovascular
disease, but the number and variety of natural drugs included are small
and insufficient, and there are no articles detailing the protective
effects of different types of natural small molecule drugs on multiple
cardiovascular diseases. Natural small molecule drugs have high
biological activity and structural diversity, and are more likely to
enter the body to exert their effects. In this article, we describe the
efficacy of such drugs for anti-atherosclerosis, cardiomyocyte repair,
and antagonism of ventricular remodeling, heart failure, and arrhythmias
to provide an experimental basis for clinical research and
identification of new therapeutic approaches.