Cytomegalovirus (CMV) is the most common congenital and perinatal viral
infection. It can occur in utero, during delivery, by blood transfusion
or by breast milk. These are usually asymptomatic in term infants due to
the presence of maternally derived, trans placental CMV (Ig)G
antibodies, but in premature neonates, can lead to severe disease
because of lack of sufficient quantities of these antibodies
1. In lactating CMV seropositive mothers, transmission
occurs in 22.8% premature infants, with symptomatic disease in 34.5%.
2 We report 3 cases of neonates with atypical CMV
infection involving lungs and requiring treatment with antivirals.