loading page

Prosthetic Valve Leaflet Perforation resulting in Critical Aortic Insufficiency: A Rare Late Complication after use of COR-KNOT
  • +1
  • Sankalp P. Patel,
  • Robert J. Cubeddu,
  • Stephen E. D’Orazio,
  • Brian J. Solomon
Sankalp P. Patel
NCH Healthcare System

Corresponding Author:[email protected]

Author Profile
Robert J. Cubeddu
NCH Healthcare System
Author Profile
Stephen E. D’Orazio
NCH Healthcare System
Author Profile
Brian J. Solomon
NCH Healthcare System
Author Profile


The implementation of automatic fasteners such as the Cor-knot ® device (LSI Solutions, Inc.) has revolutionized the field of minimally invasive valvular surgery. Nonetheless, paravalvular regurgitation, valvular embolization, and early leaflet perforation are all potential complications which may occur. Late manifestations of leaflet perforation (>5-year post-implantation) are rare. Herein, we discuss a patient who underwent remote Trifecta ® (St. Jude, Inc.) surgical aortic valve replacement (SAVR) presenting with symptomatic critical aortic regurgitation secondary to leaflet perforation from automatically fastened metallic Cor-knot ® sutures.
02 Aug 2022Submitted to Journal of Cardiac Surgery
02 Aug 2022Submission Checks Completed
02 Aug 2022Assigned to Editor
03 Aug 2022Reviewer(s) Assigned
21 Aug 2022Review(s) Completed, Editorial Evaluation Pending
22 Aug 2022Editorial Decision: Revise Minor
26 Aug 20221st Revision Received
29 Aug 2022Submission Checks Completed
29 Aug 2022Assigned to Editor
29 Aug 2022Reviewer(s) Assigned
14 Sep 2022Review(s) Completed, Editorial Evaluation Pending
19 Sep 2022Editorial Decision: Accept
02 Oct 2022Published in Journal of Cardiac Surgery. 10.1111/jocs.16983