Unveiling a multilayered regulatory network of NONEXPRESSOR OF
PATHOGENESIS-RELATED GENES1 --- A central node of salicylic
acid-mediated plant defense
Abstract
Salicylic acid (SA) plays pivotal roles in plant defense against
biotrophic and hemibiotrophic pathogens. Tremendous progress has been
made in the field of the SA biosynthesis pathways and SA-mediated plant
defense signaling networks in the past three decades. As one of the SA
receptors, NONEXPRESSOR OF PATHOGENESIS-RELATED GENES1 (NPR1) functions
as a master regulator of SA-mediated plant defense. The function of NPR1
is tightly regulated by transcriptional and post-translational
regulation. This review discusses recent advances in SA and NPR1
biology, including SA perception, SA signaling, the function of SA and
NPR1 in plant immunity, and the transcriptional and post-translational
regulation of NPR1.